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genital herpes



Genital herpes is an STD caused by HSV-1 or HSV-2, although, genital herpes is mostly caused by HSV-2. Genital herpes is a contagious viral infection affecting primarily the genitals of men and women. Genital herpes is characterized by recurrent clusters of vesicles and lesions at the genital areas or below the waist. A person usually gets HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection. Transmission may occur even if there is no visible outbreak if the infected person is shedding. While generally not dangerous, it is a nuisance and can be emotionally traumatic, as there is no cure.

Cold sores or HSV-1, the Herpes Simplex Virus Type 1, can also cause genital herpes. HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection. So having oral sex with a person who has a cold sore can cause genital herpes, having had contact with the cold sore. Keep in mind, even if a cold sore is not present, there might be asymptomatic shedding or transmission. Genital HSV-1 outbreaks recur less regularly than genital HSV-2 outbreaks.

Genital HSV-2 infection is more common in women (approximately one out of four women) than in men (almost one out of eight). This may be due to male-to-female transmission being more likely than female-to-male transmission.

Genital herpes has reached epidemic proportions in the U.S.; 500,000 are diagnosed each year. One in five American adults has herpes, but only one third of those inflicted are aware that they have the virus. Many people don't relate their symptoms to herpes, since they have either very mild or no symptoms at all. Over 50 million cases are currently estimated to exist in either the active or dormant stage.


Theory of Cause: ...Dr. C.N. Look

Herpes simplex viruses include two distinct but closely related viruses, namely, HSV-1 and HSV-2. Both viruses can cause genital herpes. Roughly speaking, HSV-2 causes 90% and HSV-1 causes 10% of all genital herpes. Herpes simplex virus is a linear double-stranded DNA virus. HSV-1 and HSV-2 share approximately 50% homology of their genetic materials and they even express type-common surface antigens. It accounts for the high degree of cross-reactivity and the technical difficulty in differentiating the 2 viruses. On the other hand, HSV-1 & HSV-2 antibodies offer some degree of cross protection. Cell-mediated immune responses is more important than humoral responses in determining the severity of HSV infections. Hence, AIDS patients often have chronic and severe anogenital herpes. Genital herpes is usually transmitted by sexual intercourse. Direct inoculation of virus occurs through contact with infected secretions or mucosal surfaces. Orogenital contact with a partner with type 1 herpes labialis can also result in genital herpes. Asymptomatic shedding of HSV is the most common mode of transmission of genital herpes infection. It is estimated that more than half of the HSV-2 genital infections are asymptomatic.


FACTS ABOUT GENITAL HERPES:

Transmission is caused by close oral, anal, or genital contact, including intercourse, masturbation, kissing, or any direct skin-to-skin contact which allows for the transfer of bodily fluids.

A person is considered contagious when prodromal symptoms, active sores, and healing lesions are present.

Herpes is potentially contagious when no symptoms are present. That is, a person who has genital herpes is potentially always shedding active virus.

Approximately 1 in 6 members of the general infected population is thought to shed active virus occasionally without symptoms.

Some people do not get typical blister-like sores but harbor active virus in their saliva, vaginal, or penile secretions, and can shed the virus without knowing they have herpes.

Lesions can occur deep inside the vagina where they cannot be seen or felt, but can readily transmit the virus.

An uninfected individual has about a 75% chance of contracting herpes during intimate contact with someone actively shedding virus.

Oral herpes can be transmitted to the genitals, and vice versa. Symptoms are similar.

Auto-inoculation: An infected individual can spread the virus to other parts of his or her body by touching an area shedding virus and then touching, scratching, or rubbing another susceptible part of the body. Towels are especially conducive to this.

It is possible for a person to contract genital herpes if the partner with oral herpes performs oral sex. Oral herpes can be transmitted to the genitals, and vice versa. Symptoms are similar.

Environmental surfaces like toilet seats may be a source of contagion, but there is no evidence that this poses a real threat to the general population. Experts differ as to how long the virus can survive on its own. The primary cause of infection remains intimate contact.

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